Human-Disease Phenotype Map

This page contains Disease-disease networks generated from various PheWAS datasets.     

PlaceholderMeta EUR

European ancestry

This is a phenotype association network for meta-analyzed PheWAS summary data from FinnGen, the Million Veteran Program, and the UK Biobank in individuals genetically similar to European ancestry. Edges connect traits that are genetically correlated.


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PlaceholderMeta AFR

African ancestry

This is a phenotype association network for meta-analyzed PheWAS summary data from the Million Veteran Program and the UK Biobank in individuals genetically similar to African ancestry. Edges connect traits that are genetically correlated.



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PlaceholderMeta EAS

East asian ancestry

This is a phenotype association network for meta-analyzed PheWAS summary data from Biobank Japan, the Korean Genome and Epidemiology Study, the Million Veteran Program, the Tohoku Medical Megabank, and the UK Biobank in individuals genetically similar to East Asian ancestry. Edges connect traits that are genetically correlated.

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PlaceholderMeta AMR

American ancestry

This is a phenotype association network for meta-analyzed PheWAS summary data from the Million Veteran Program and the UK Biobank in individuals genetically similar to American ancestry. Edges connect traits that are genetically correlated.

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PlaceholderFinnGen

European ancestry

This is a disease association network for PheWAS summary data from the FinnGen. Edges connect phenotypes that are genetically correlated.



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PlaceholderUKBB MaleDDN

European ancestry

This is a disease-disease network for male-stratified PheWAS summary data from the UK Biobank.




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PlaceholderUKBB FemaleDDN

European ancestry

This is a disease-disease network for female-stratified PheWAS summary data from the UK Biobank.



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PlaceholderBiomarkerDDN

European ancestry

This is a disease-disease network for PheWAS summary data from the UK Biobank. Nodes are colored by PheCode category and sized by degree. Edges connect phenotypes that are correlated with the same labeled biomarkers

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PlaceholderUKBB

European ancestry

Disease-disease network generated by using PheWAS data from UK BioBank PheWAS results obtained from https://www.leelabsg.org/resources


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PlaceholderUKBBSigned DDN

European ancestry

Disease-disease network generated by using PheWAS data from UK BioBank PheWAS results obtained from https://www.leelabsg.org/resources. Disease associations were determined by accounting for the direction of effects of genetic components.

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PlaceholderGENIE

Korean ancestry

Disease-disease network generated by using PheWAS data from Gene-environmental interaction and phenotype (GENIE) cohort results.



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PlaceholderDiscovEHR

European ancestry

Disease-disease network generated by using PheWAS data from DiscovEHR study (Geisinger Health System & Regeneron Genetics Center).



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